USP5 MOTIVATES IMMUNOSUPPRESSIVE MICROENVIRONMENT IN MULTIPLE MYELOMA BY ACTIVATING STAT2-PFKFB4-MEDIATED GLYCOLYSIS

USP5 motivates immunosuppressive microenvironment in multiple myeloma by activating STAT2-PFKFB4-mediated glycolysis

Abstract Background Glycolysis, a classic characteristic of cancer cells, can drive cancer progression by generating lactate, which play as a key immunosuppressive mediator.Currently, ubiquitin-specific proteases 5 (USP5) has been demonstrated to facilitate tumor cell survival in multiple myeloma (MM), whereas whether USP5 was involved in glycolysi

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Quality Analysis of Sugarcane Plant Water by Nanofiltration During the Processing of Membrane-Process Brown Sugar

In order to study the quality and development value of nanofiltration liquid (sugarcane plant water, SPW) by the No-added brown sugar from membrane processing, red peel fruit sugarcane and ROC 22 were used as materials to evaluate the nutritional quality with the method of index of nutritional quality (INQ), which could be obtained by comparing and

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